Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2624
Gene Symbol: GATA2
GATA2 		0.800 Biomarker group GENOMICS_ENGLAND The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia. 27069254 2016
Entrez Id: 54790
Gene Symbol: TET2
TET2 		0.800 Biomarker group GENOMICS_ENGLAND
Entrez Id: 171023
Gene Symbol: ASXL1
ASXL1 		0.800 Biomarker group GENOMICS_ENGLAND Recent advances in understanding clonal haematopoiesis in aplastic anaemia. 28107566 2017
Entrez Id: 2624
Gene Symbol: GATA2
GATA2 		0.800 Biomarker group GENOMICS_ENGLAND Pathological mutations were present in DKC1, MPL, and TP53 among the aplastic anemia cohort, and in FANCA, GATA2, MPL, RTEL1, RUNX1, SBDS, TERT, TINF2, and TP53 among the myelodysplastic syndrome cohort. 27418648 2016
Entrez Id: 2624
Gene Symbol: GATA2
GATA2 		0.800 Biomarker group GENOMICS_ENGLAND We found the same, previously unidentified heterozygous c.1061C>T (p.Thr354Met) missense mutation in the GATA2 transcription factor gene segregating with the multigenerational transmission of MDS-AML in three families and a GATA2 c.1063_1065delACA (p.Thr355del) mutation at an adjacent codon in a fourth MDS family. 21892162 2011
Entrez Id: 171023
Gene Symbol: ASXL1
ASXL1 		0.800 Biomarker group GENOMICS_ENGLAND
Entrez Id: 2624
Gene Symbol: GATA2
GATA2 		0.800 Biomarker group GENOMICS_ENGLAND
Entrez Id: 23451
Gene Symbol: SF3B1
SF3B1 		0.800 Biomarker group GENOMICS_ENGLAND
Entrez Id: 2624
Gene Symbol: GATA2
GATA2 		0.800 Biomarker group GENOMICS_ENGLAND Mutations in GATA2 cause primary lymphedema associated with a predisposition to acute myeloid leukemia (Emberger syndrome). 21892158 2011
Entrez Id: 51119
Gene Symbol: SBDS
SBDS 		0.620 Biomarker group GENOMICS_ENGLAND Germline Genetic Predisposition to Hematologic Malignancy. 28297620 2017
Entrez Id: 2187
Gene Symbol: FANCB
FANCB 		0.500 Biomarker group GENOMICS_ENGLAND Germline Genetic Predisposition to Hematologic Malignancy. 28297620 2017
Entrez Id: 5888
Gene Symbol: RAD51
RAD51 		0.460 Biomarker group GENOMICS_ENGLAND Germline Genetic Predisposition to Hematologic Malignancy. 28297620 2017
Entrez Id: 7516
Gene Symbol: XRCC2
XRCC2 		0.420 Biomarker group GENOMICS_ENGLAND Germline Genetic Predisposition to Hematologic Malignancy. 28297620 2017
Entrez Id: 2177
Gene Symbol: FANCD2
FANCD2 		0.410 Biomarker group GENOMICS_ENGLAND Germline Genetic Predisposition to Hematologic Malignancy. 28297620 2017
Entrez Id: 2072
Gene Symbol: ERCC4
ERCC4 		0.410 Biomarker group GENOMICS_ENGLAND Germline Genetic Predisposition to Hematologic Malignancy. 28297620 2017
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.410 Biomarker group GENOMICS_ENGLAND Germline Genetic Predisposition to Hematologic Malignancy. 28297620 2017
Entrez Id: 79728
Gene Symbol: PALB2
PALB2 		0.400 Biomarker group GENOMICS_ENGLAND Germline Genetic Predisposition to Hematologic Malignancy. 28297620 2017
Entrez Id: 2188
Gene Symbol: FANCF
FANCF 		0.400 Biomarker group GENOMICS_ENGLAND Germline Genetic Predisposition to Hematologic Malignancy. 28297620 2017
Entrez Id: 10459
Gene Symbol: MAD2L2
MAD2L2 		0.400 Biomarker group GENOMICS_ENGLAND Germline Genetic Predisposition to Hematologic Malignancy. 28297620 2017
Entrez Id: 57697
Gene Symbol: FANCM
FANCM 		0.400 Biomarker group GENOMICS_ENGLAND Germline Genetic Predisposition to Hematologic Malignancy. 28297620 2017
Entrez Id: 83990
Gene Symbol: BRIP1
BRIP1 		0.400 Biomarker group GENOMICS_ENGLAND Germline Genetic Predisposition to Hematologic Malignancy. 28297620 2017
Entrez Id: 2189
Gene Symbol: FANCG
FANCG 		0.400 Biomarker group GENOMICS_ENGLAND Germline Genetic Predisposition to Hematologic Malignancy. 28297620 2017
Entrez Id: 55120
Gene Symbol: FANCL
FANCL 		0.400 Biomarker group GENOMICS_ENGLAND Germline Genetic Predisposition to Hematologic Malignancy. 28297620 2017
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		0.400 Biomarker group GENOMICS_ENGLAND Germline Genetic Predisposition to Hematologic Malignancy. 28297620 2017
Entrez Id: 2178
Gene Symbol: FANCE
FANCE 		0.400 Biomarker group GENOMICS_ENGLAND Germline Genetic Predisposition to Hematologic Malignancy. 28297620 2017